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Plasma donation · South Dakota

Plasma donation centers in South Dakota

Every plasma center we track in South Dakota, with its hours and what it pays new donors. Pick a city below, or search your ZIP to sort them by distance.

1centers we list
1city
$800top new-donor offer (up to)

Rapid City (1)

  • CSL Plasma

    1555 Haines Ave, Rapid City, SD 57701

    Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.

    Mon–Fri 7am–7pm · Sat 7am–3pm · Sun closed

Don't see your center?

We list the centers we can read from each company's own website, so new or recently moved centers can be missing. Check the company's own locator:

Before you go

Your first visit, sorted

Most "up to" bonuses need several donations inside the first month or so, and you can donate at most twice in any 7 days, with a day between. Ask the center for the exact terms.

  • Prep the day beforeDrink lots of water, eat a protein- and iron-rich meal 3+ hours before, and skip alcohol.
  • Bring theseA valid photo ID (18+), proof of address like recent mail or a lease, and proof of your Social Security number.
  • Plan your timeThe first visit takes 2 to 3 hours because of the health screening. Return visits take about 1 to 2 hours.

Common questions

Plasma in South Dakota, answered

Quick answers before your first visit.

How many plasma centers are in South Dakota?

We list 1 plasma donation center in South Dakota: 1 CSL Plasma. Centers open, close and move, so check the company's own locator too if you don't see one you know about.

How much do plasma centers in South Dakota pay new donors?

The highest new-donor offer we found here is "Up to $800 in your first month" at CSL Plasma in Rapid City. Offers are "up to" amounts, paid across several donations, and they change often, so confirm the terms with the center.

Are any plasma centers in South Dakota open on Sunday?

None of the centers we list here show Sunday hours right now. Most are open on Saturday, so check each center's hours above.

What do I need to bring to donate plasma?

Bring a valid photo ID, proof of your address (like recent mail or a lease), and proof of your Social Security number (like your card, a W-2 or a pay stub). You generally need to be at least 18 and weigh at least 110 pounds.

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