Plasma donation · South Carolina
Plasma donation centers in South Carolina
Every plasma center we track in South Carolina, with its hours and what it pays new donors. Pick a city below, or search your ZIP to sort them by distance.
Columbia (4)
Columbia page ›CSL Plasma
215 Assembly Street, Columbia, SC 29201
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–7pm · Sat 8am–3pm · Sun closed
CSL Plasma
2768 Decker Blvd, Suite 300A, Columbia, SC 29206
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–7pm · Sat, Sun 7am–3pm
Octapharma Plasma
10 Gateway Corners Park, Ste 100, Columbia, SC 29203
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Sun 6am–6pm
Octapharma Plasma
7535 Garners Ferry Rd, Ste G, Columbia, SC 29209
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Sun 8am–5pm
Spartanburg (3)
Spartanburg page ›CSL Plasma
630 Chesnee Hwy;, Unit 3, Spartanburg, SC 29303
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–7pm · Sat, Sun 7am–3pm
Octapharma Plasma
1000 N Pine St, #24B, Spartanburg, SC 29303
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Fri 7am–7pm · Sat, Sun 9am–6pm
BioLife Plasma Services
120 Dorman Commerce Dr, Ste I, Spartanburg, SC 29301
Up to $600 in your first monthFrom this center's own page, checked October 26, 2026. Can change.Tue–Thu 6am–7pm · Fri 6am–6:30pm · Sat, Sun 7am–3pm · Mon closed
Greenville (2)
CSL Plasma
3221 W. Blue Ridge Drive, Greenville, SC 29611
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–6:30pm · Sat, Sun 7am–3pm
BioLife Plasma Services
1469 Woodruff Rd, Greenville, SC 29607
Up to $700 in your first monthFrom this center's own page, checked October 26, 2026. Can change.Mon 11am–7pm · Tue–Thu 6am–7pm · Fri 6am–6pm · Sat, Sun 7am–3pm
Charleston (1)
Octapharma Plasma
5900 Rivers Ave, Suite F, Charleston, SC 29406
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Sun 7am–7pm
Florence (1)
Octapharma Plasma
1825 W Palmetto St, Florence, SC 29501
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Sat 7am–7pm · Sun 9am–4pm
North Charleston (1)
CSL Plasma
7800 Rivers Ave, Suite 1620, North Charleston, SC 29406
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–7pm · Sat, Sun 7am–3pm
Orangeburg (1)
Octapharma Plasma
1450 Chestnut St, Orangeburg, SC 29115
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Fri 6am–6pm · Sat, Sun 9am–6pm
Rock Hill (1)
CSL Plasma
1807 Cherry Road, Suite 129, Rock Hill, SC 29732
Up to $800 in your first monthCompany-wide "up to" figure, checked October 26, 2026. Varies by location and can change.Mon–Fri 6am–7pm · Sat, Sun 7am–3pm
Sumter (1)
Octapharma Plasma
225 N Washington St, Sumter, SC 29150
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Fri 7am–7pm · Sat, Sun 9am–6pm
West Columbia (1)
Octapharma Plasma
1618 Charleston Hwy, West Columbia, SC 29169
Up to $750 in your first 35 daysCompany-wide "up to" figure, checked October 22, 2026. Varies by location and can change.Mon–Sun 6:30am–6:30pm
Don't see your center?
We list the centers we can read from each company's own website, so new or recently moved centers can be missing. Check the company's own locator:
Before you go
Your first visit, sorted
Most "up to" bonuses need several donations inside the first month or so, and you can donate at most twice in any 7 days, with a day between. Ask the center for the exact terms.
- Prep the day beforeDrink lots of water, eat a protein- and iron-rich meal 3+ hours before, and skip alcohol.
- Bring theseA valid photo ID (18+), proof of address like recent mail or a lease, and proof of your Social Security number.
- Plan your timeThe first visit takes 2 to 3 hours because of the health screening. Return visits take about 1 to 2 hours.
Common questions
Plasma in South Carolina, answered
Quick answers before your first visit.
How many plasma centers are in South Carolina?
We list 16 plasma donation centers in South Carolina: 8 Octapharma Plasma, 6 CSL Plasma, and 2 BioLife Plasma Services. Centers open, close and move, so check the company's own locator too if you don't see one you know about.
How much do plasma centers in South Carolina pay new donors?
The highest new-donor offer we found here is "Up to $800 in your first month" at CSL Plasma in Columbia. Offers are "up to" amounts, paid across several donations, and they change often, so confirm the terms with the center.
Are any plasma centers in South Carolina open on Sunday?
15 of the 16 centers we list show Sunday hours: BioLife Plasma Services in Greenville, BioLife Plasma Services in Spartanburg, CSL Plasma in Columbia, and CSL Plasma in Greenville and 11 more. Hours can change on holidays, so check before you go.
What do I need to bring to donate plasma?
Bring a valid photo ID, proof of your address (like recent mail or a lease), and proof of your Social Security number (like your card, a W-2 or a pay stub). You generally need to be at least 18 and weigh at least 110 pounds.
Somewhere else?
Cities in South Carolina, or another state
Search any city or ZIP to see the closest centers on a map, with today's hours.